Vildagliptin Powder yog dab tsi?
piav qhia:
Vildagliptin (LAF-237; NVP-LAF 237) inhibits DPP-4 nrog IC50 ntawm 2.3 nM. IC50 tus nqi: 2.3 nM[1] Lub Hom Phiaj: DPP-4 Hauv vitro: Vildagliptin yog N-hloov glycyl-2-cyanopyrrolidine (Daim duab 2). Nws yog ib qho muaj zog, sib tw thiab thim rov qab inhibitor ntawm DPP-4 hauv vitro thiab hauv cov nas nrog qhov nruab nrab inhibitory concentration (IC50) ntawm ~{17}} nmol / L. Qhov tseem ceeb, vildagliptin inhibits DPP-4 nrog qhov tshwj xeeb siab piv rau lwm cov peptidases zoo sib xws nrog IC50s tshaj 200 mol / L.
Cov yam ntxwv yooj yim
274901-16-5
C17H25N3O2
303.39900
303.19500
76.36000
1.50308
Yam ntxwv
dawb crystalline hmoov
1.27 g / cm3
153-155 degree
531.3ºC ntawm 760 mmHg
275.1ºC
Cov ntaub ntawv kev nyab xeeb
2933990090
24/25-26-28-36/37/39
Kev siv
Vildagliptin (yav tas los LAF237, lub npe lag luam Galvus, Zomelis,) yog ib qho tshuaj tiv thaiv qhov ncauj los tiv thaiv hyperglycemic (cov tshuaj tiv thaiv ntshav qab zib) ntawm cov tshuaj tshiab dipeptidyl peptidase -4 (DPP-4) inhibitor chav kawm ntawm cov tshuaj. Vildagliptin inhibits qhov tsis ua haujlwm ntawm GLP-1 thiab GIP los ntawm DPP-4, tso cai rau GLP-1 thiab GIP los ua kom muaj zog tso tawm ntawm insulin hauv beta hlwb thiab txo qis glucagon tso tawm los ntawm alpha hlwb ntawm lub hlwb. Cov islets ntawm Langerhans nyob rau hauv pancreas.Vildagliptin tau pom tias txo qis hyperglycemia hauv hom 2 mob ntshav qab zib mellitus.
Tuam Tshoj Vildagliptin Export Cov ntaub ntawv
Cov ntaub ntawv hais los ntawm General Administration of Customs, PRChina
2018.11-2019.11 Tuam Tshoj Vildagliptin Export Data
