Lidocaine yog dab tsi?
Lidocaineyog ib qho tshuaj loog hauv zos thiab tshuaj tiv thaiv arrhythmia. Nws yog ib qho derivative ntawm cocaine, tab sis tsis muaj ib qho ntawm cov tshuaj lom neeg thiab cov khoom xyaw ntawm cov yeeb tshuaj yeeb. Lidocaine hydrochloride yog dawb crystalline hmoov, uas yog me ntsis yaj hauv dej. Nws cov tshuaj toxicity zoo ib yam li procaine, tab sis cov nyhuv ntawm cov tshuaj loog hauv zos muaj zog thiab kav ntev, nrog rau qhov chaw zoo. Nws tuaj yeem raug txhaj lossis siv ua tshuaj loog saum npoo. Lidocaine yog ib qho tshuaj loog zoo heev uas siv tau ib mus rau peb feeb tom qab thov thiab kav ib mus rau peb teev. Siv los kho cov kab mob canker. Nws tau raug siv tsawg dua li cov tshuaj tiv thaiv kab mob plawv vim muaj kev txhawj xeeb txog kev phiv mus ntev. Qee tus neeg ua xua rau lidocaine. Xyoo 1963, nws tau siv rau kev kho mob arrhythmia. Nws yog cov tshuaj rau kev tiv thaiv thiab kho mob myocardial infarction thiab ntau yam kab mob hauv lub plawv nyuaj nrog ceev ventricular arrhythmia. Nws yog thawj qhov kev xaiv rau lub sijhawm ntxov ventricular yeej, ventricular tachycardia thiab ventricular tremor ntawm mob myocardial infarction.
Cov khoom no yog ib qho tshuaj loog hauv zos amide. Tom qab kev nqus ntshav los yog kev tswj hwm hauv cov hlab ntsha, lub hauv nruab nrab lub paj hlwb muaj qhov pom tseeb excitatory thiab inhibitory biphasic nyhuv, thiab tsis tuaj yeem ua rau tsis muaj kev zoo siab, thaum cov ntshav cov tshuaj concentration tsawg, analgesia thiab lethargy, mob pib nce; Nrog rau kev siv tshuaj ntau ntxiv, cov nyhuv lossis toxicity yog txhim kho, subtoxic ntshav concentration muaj cov nyhuv anticonvulsant; Convulsion yuav tshwm sim thaum lub plasma concentration ntau tshaj 5mg·ml-1. Ntawm qhov koob tshuaj tsawg, cov khoom no tuaj yeem txhawb nqa K ntxiv rau kev tawm hauv cov hlwb myocardial, txo qhov kev qhuab qhia ntawm tus kheej ntawm myocardium, thiab muaj cov nyhuv anti-ventricular arrhythmia; Tsis muaj qhov cuam tshuam tseem ceeb ntawm kev ua haujlwm hluav taws xob ntawm cov hlwb myocardial, atrioventricular conduction thiab myocardial contraction ntawm koob tshuaj. Ntshav cov tshuaj concentration nce ntxiv, tuaj yeem ua rau lub plawv dhia nrawm nrawm, atrioventricular conduction thaiv, inhibit myocardial contractility thiab ua rau lub plawv tsis ua haujlwm.
Yog tias koj muaj lus nug txoglidocaine, tsuas yog tiv tauj peb ntawm email:info@haozbio.com
