Dosage and Precautions for Amikacin Siv
Kev siv thiab ntau npaum li cas
1. Cov neeg laus txhaj tshuaj intramuscular lossis intravenous drip, urinary tract infection, 0.25g txhua 12 teev; Rau lwm cov kab mob hauv lub cev, 5mg / kg ib 8 teev lossis 7.5mg / kg ib 12 teev ntawm lub cev hnyav. Cov neeg laus yuav tsum tsis txhob ntau tshaj 1.5g ib hnub twg thiab cov kev kho mob yuav tsum tsis txhob ntau tshaj 10 hnub.
2. Thawj koob tshuaj txhaj tshuaj intramuscular lossis intravenous drip yog 10mg / kg, ua raws li 7.5mg / kg txhua 12 teev; Cov menyuam yaus siv tib yam li cov neeg laus.
3. Kev txhaj tshuaj intramuscular lossis intravenous drip, 15mg / kg ib hnub twg, muab nyob rau hauv 2-3 zaug, txhua hnub koob tshuaj ntawm cov neeg laus yuav tsum tsis pub tshaj 1.5g. Rau cov kab mob urinary yooj yim, 250 mg tuaj yeem siv ob zaug ib hnub. Cov menyuam mos liab siv 10mg / kg thawj zaug thiab 7.5mg / kg txhua 12 teev tom qab ntawd. Feem ntau, kev kho mob tsis pub dhau 10 hnub.
Kev phiv tshuaj
1. Nws feem ntau cuam tshuam rau cov hlab ntsha cochlear, ua rau tus neeg mob lub pob ntseg hnov ntau zaus raug puas tsuaj ua ntej, thiab tom qab ntawd qhov tsis hnov lus maj mam nce mus rau lag ntseg, tinnitus thiab kev xav ntawm pob ntseg puv.
2. Nephrotoxicity: Nws feem ntau ua rau lub raum lub raum puas, uas yuav ua rau cov proteinuria thiab tubular tso zis, tom qab ntawd hematuria, txo qis los yog nce zis ntim, thiab tom qab ntawd mus rau azotemia, txo lub raum ua haujlwm, nce poov tshuaj excretion, thiab lwm yam.
3. Neuromuscular block: amikacin muaj cov nyhuv thaiv ntawm acetylcholine thiab complexing calcium ions zoo ib yam li curcumin, thiab tuaj yeem ua rau myocardial inhibition, ua pa tsis ua haujlwm, thiab lwm yam. Cov neeg mob uas muaj myasthenia qub lossis cov uas tau txais cov nqaij ntshiv yog feem ntau tshwm sim.
4. Kev tsis haum tshuaj: Qee tus neeg mob yuav muaj kev tsis haum tshuaj tom qab noj tshuaj, suav nrog anaphylactic shock, pob khaus, urticaria, tshuaj kub cev, thiab lwm yam.
5. Lwm tus: Amikacin tuaj yeem cuam tshuam rau cov nroj tsuag ib txwm muaj, thiab siv sijhawm ntev tuaj yeem ua rau muaj kab mob loj hlob ntau dhau.
Cov teeb meem xav tau kev saib xyuas
1. Kev poob dej tuaj yeem ua rau muaj cov tshuaj ntshav ntau ntxiv thiab ua rau muaj kev phom sij txaus ntshai.
2. Qhov thib yim yog lub paj hlwb puas tsuaj, vim tias cov khoom no tuaj yeem ua rau vestibular paj thiab auditory paj puas.
3. Myasthenia gravis lossis Parkinson's disease tuaj yeem ua rau cov hlab ntsha hauv lub cev, ua rau cov leeg pob txha tsis muaj zog.
4. Yog tias lub raum ua haujlwm puas lawm, cov khoom yog nephrotoxic.
5. Kev cuam tshuam nrog kev kuaj mob Cov khoom no tuaj yeem nce qhov ntsuas qhov tseem ceeb ntawm alanine aminotransferase (ALT), aspartate aminotransferase (AST), serum bilirubin concentration thiab lactate dehydrogenase concentration; Qhov ntsuas ntawm cov ntshav calcium, magnesium, potassium thiab sodium concentrations yuav txo qis.
6. Aminoglycosides thiab Kev sib xyaw ntawm lactams (cephalosporins thiab penicillins) tuaj yeem ua rau muaj kev sib koom ua ke. Thaum cov khoom no siv ua ke nrog cov tshuaj tua kab mob saum toj no, nws yuav tsum tau muab tso rau hauv lub raj mis. Amikacin yuav tsum tsis txhob txhaj nrog lwm cov tshuaj hauv tib lub raj mis.
7. Cov neeg mob yuav tsum tau muab dej txaus kom txo tau lub raum tubular puas.
8. Thaum npaj cov tshuaj tua kab mob, ntxiv 100 ~ 200mL ntawm sodium chloride txhaj lossis 5 feem pua ntawm cov piam thaj los yog lwm yam tshuaj tsis muaj menyuam txhua 500mg. Cov neeg laus yuav tsum tau maj mam infused nyob rau hauv 30 mus rau 60 feeb, thiab lub ntim ntawm diluted kua nyob rau hauv cov me nyuam mos yuav tsum tau txo kom raws li.
Kev siv tshuaj rau cov poj niam cev xeeb tub thiab cov poj niam lactating: Cov khoom no yog nyob rau hauv Class D ntawm kev siv tshuaj rau cov poj niam cev xeeb tub, uas yog, nws muaj qee yam kev puas tsuaj rau tib neeg, tab sis cov txiaj ntsig yuav ntau dua qhov tsis zoo tom qab siv tshuaj. Cov khoom no tuaj yeem dhau los ntawm cov placenta thiab ncav cuag cov ntaub so ntswg hauv plab, uas tuaj yeem ua rau lub cev tsis hnov lus tsis zoo. Cov poj niam cev xeeb tub yuav tsum ntsuas qhov zoo thiab qhov tsis zoo ua ntej siv cov khoom no. Cov poj niam pub niam mis yuav tsum tsis txhob pub mis niam thaum noj tshuaj.
Kev siv tshuaj rau cov menyuam yaus: aminoglycosides yuav tsum tau siv nrog ceev faj hauv kev kho menyuam yaus, tshwj xeeb tshaj yog cov menyuam mos ntxov ntxov thiab cov menyuam yug tshiab uas nws lub raum tsis tau tsim tag nrho, uas ua rau ntev ib nrab-lub neej ntawm cov tshuaj zoo li no, thiab cov tshuaj yooj yim rau hauv lub cev. thiab tsim cov tshuaj lom neeg.
Kev siv tshuaj rau cov neeg laus: Lub raum ua haujlwm ntawm cov neeg laus laus muaj qee qhov kev poob qis ntawm lub cev. Txawm hais tias qhov ntsuas tus nqi ntawm lub raum ua haujlwm nyob rau hauv ib txwm muaj, kev kho me me yuav tsum tseem siv. Cov neeg laus muaj kev pheej hmoo ua rau muaj ntau yam tshuaj lom tom qab siv cov khoom no, yog li ntshav cov tshuaj concentration yuav tsum tau saib xyuas kom ntau li ntau tau thaum lub sijhawm kho.
