Puas yog Resveratrol Puas Ua Haujlwm?

Puas yog resveratrol ua haujlwm tiag tiag?
Txij li thaum nws qhov kev sib cais los ntawm cov hauv paus hniav ntawm Veratrumgrandiflorum O. Loes hauv xyoo 1940, cov kws tshawb fawb tau pom cov tshuaj nquag no hauv ntau cov nroj tsuag (cov tshuaj no muaj nyob rau hauv plaub chav kawm tseem ceeb: isoflavones isoflavonoids, flavonoids flavonoids, butyl ether stilbenes thiab lignans lignans yog restilated), . nws thiab nws cov glucoside glycosides muaj txiaj ntsig zoo rau tib neeg kev noj qab haus huv thiab tau pom tias muaj cov tshuaj tiv thaiv kab mob antioxidant, tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kab mob thiab estrogenic / anti-estrogenic kev ua ub no. Resveratrol tsis tsuas pom muaj nyob rau hauv liab caw, tab sis kuj nyob rau hauv ntshav thiab liab txiv hmab txiv ntoo, blueberries, cranberries, mulberruy, lingonberries, txiv laum huab xeeb, pistachios, thiab Japanese tiger cag knotweed (ib tug anti-inflammatory thiab antiplatelet neeg sawv cev nyob rau hauv Nyiv). Cov tshuaj no yog tsim los ntawm cov nroj tsuag los tua cov kab mob, fungi thiab lwm yam kab mob, tiv thaiv ultraviolet hluav taws xob thiab kom ntseeg tau tias cov nroj tsuag muaj sia nyob hauv qhov xwm txheej!

Yog li qhov twg resveratrol rho tawm los ntawm hnub no? Tsis yog, tsis muaj! Nws yog muab rho tawm los ntawm brewer cov poov xab Saccharomyces cerevisiae los ntawm cov tshuaj los yog biotechnological synthesis.

Xyoo 2003, xib fwb David Sinclair pab neeg ntawm Harvard Medical School tau luam tawm lawv thawj qhov kev tshawb pom tias resveratrol nce cell ciaj sia taus thiab qeeb kev laus hauv cov poov xab (thiab tom qab ntawd hauv nas) los ntawm kev ua kom muaj "ntev" noob hu ua SIRT1. Ib qho kev xav ntawm kev tshawb fawb yog tias resveratrol tig rau ntawm cov caj ces uas ua rau sirtuins (cov proteins thaum ub pom nyob rau hauv txhua hom), ua kom tsis muaj zog ntawm kev tswj hwm cov proteins thiab cov noob uas tau cai rau lawv, yog li pib cov lus teb los tua kab mob thiab ua kom lub neej ntev.
Hauv cov kev tshawb fawb tom qab hauv cov nas, resveratrol tau pom los tiv thaiv kab mob qog noj ntshav, tiv thaiv ntshav siab thiab kab mob plawv, txhim kho insulin rhiab heev ntawm kev noj zaub mov muaj rog, txo cov ntshav qab zib thiab rog, thiab tiv thaiv cov hlab ntsha thiab lub hlwb ntawm cov tsiaj kuaj.
Txawm li cas los xij, ib yam uas yuav tsum nco ntsoov yog qhov koob tshuaj ntawm resveratrol hauv kev sim yog ib txwm siab dua li cov resveratrol noj hauv cov zaub mov txhua hnub. Cov koob tshuaj uas txhim kho kev noj qab haus huv ntawm cov nas yog yuav luag sib npaug li 100 rau 1,000 khob cawv liab.

Prof Sinclair kuj tau taw qhia tias cov tuam txhab tshuaj tam sim no tau tsim ntau txhiab tus tshiab hluavtaws molecules raws li qhov kev xav no, uas yog ib txhiab npaug zoo dua li resveratrol.

Yuav ua li cas txog kev tshawb fawb hauv tib neeg?
Ib tsab xov xwm 2014 hauv JAMA Internal Medicine los ntawm Johns Hopkins University Tsev Kawm Ntawv Tshuaj Kho Mob tau tshuaj xyuas cov qib ntawm resveratrol ib txwm muaj nyob hauv cov zaub mov hauv cov zaub mov ntawm kwv yees li 800 tus txiv neej thiab poj niam hnub nyoog 65 xyoos thiab tshaj, thiab qib ntawm resveratrol metabolised hauv lawv cov zis, cia siab tias yuav kom pom cov qib siab ntawm resveratrol hauv cov neeg noj qab haus huv.

Ntau qhov kev tshawb fawb tib neeg ua ntej ntawm hom 2 mob ntshav qab zib zoo li txhawb nqa cov txiaj ntsig ntawm resveratrol hauv kev txhim kho cov ntshav qab zib thiab txo qis cov tshuaj insulin. Txawm li cas los xij, thaum saib cov kev tshawb fawb no, kuv tau pom dua tias lawv txhua tus suav nrog cov neeg siv tshuaj, yog li xav tau kev tshawb fawb ntxiv kom paub tseeb tias cov ntshav qab zib txhim kho los ntawm resveratrol lossis cov tshuaj.

Ob peb qhov kev sim tshuaj ntsuam xyuas tau saib cov cim qhia txog kev lom neeg xws li qib ntawm cov tshuaj tiv thaiv kab mob antioxidant, lub plawv dhia hloov pauv, cov ntshav ntws mus rau lub hlwb thiab tus nqi ntawm cov qog nqaij hlav cancer.
Saib rov qab los ntawm kev tshawb fawb ntawm resveratrol, peb pom tias nws feem ntau txwv rau kev tshawb fawb microbiological, tsiaj thiab cellular (cell kab lis kev cai los yog poov xab, txiv hmab txiv ntoo yoov, luv luv turquoise flounder los yog nas).