Kev Siv Thiab Kev Siv Oseltamivir

Oseltamivir phosphate tuaj yeem noj nrog zaub mov lossis cais. Txawm li cas los xij, rau qee tus neeg mob, kev noj tshuaj tib lub sijhawm tuaj yeem txhim kho kev mob siab rau tshuaj.
Kev kho mob khaub thuas:
Kev kho mob yuav tsum pib rau thawj hnub lossis thib ob (zoo tshaj li 36 teev) ntawm qhov pib ntawm tus mob khaub thuas.
1. Kev qhia noj tshuaj
Cov neeg laus thiab cov tub ntxhais hluas:
Qhov pom zoo koob tshuaj ntawm oseltamivir phosphate capsules rau cov neeg laus thiab cov tub ntxhais hluas hnub nyoog tshaj 13 xyoos yog 75 mg ib zaug, ob zaug ib hnub, rau 5 hnub.
Kev tiv thaiv kab mob khaub thuas
Qhov pom zoo koob tshuaj ntawm oseltamivir phosphate rau kev tiv thaiv kab mob khaub thuas tom qab kev sib raug zoo nrog cov neeg mob khaub thuas yog 75 mg, ib hnub ib zaug, tsawg kawg 10 hnub. Cov tshuaj yuav tsum tau pib ua ntej 2 hnub tom qab kev sib raug zoo. Qhov pom zoo koob tshuaj oseltamivir phosphate rau kev tiv thaiv kab mob khaub thuas hauv lub caij ua npaws yog 75 mg, ib hnub ib zaug. Qee cov ntaub ntawv qhia tias cov tshuaj muaj kev nyab xeeb thiab siv tau rau 6 lub lis piam. Nws muaj kev tiv thaiv zoo thaum siv tshuaj.
2. Kev taw qhia tshuaj rau cov neeg tshwj xeeb
Cov neeg mob lub raum tsis txaus:
Kev kho mob khaub thuas: tsis tas yuav kho cov koob tshuaj rau cov neeg mob uas muaj creatinine tshem tawm ntau dua 60 ml / min. Rau cov neeg uas nws qhov kev tshem tawm creatinine ntau dua 30ml / min tab sis tsis ntau dua 60ml / min, qhov pom zoo noj yog txo rau 30mg ib zaug, ob zaug ib hnub, rau tag nrho 5 hnub. Rau cov neeg uas nws qhov kev tshem tawm creatinine ntau dua 10ml / min tab sis tsis ntau dua 30ml / min, qhov pom zoo noj yog txo rau 30mg txhua zaus, ib zaug ib hnub, rau tag nrho 5 hnub. Rau cov neeg mob hemodialysis li niaj zaus, yog tias cov tsos mob khaub thuas hnyav dua li ntawm 48 teev thaum lub sij hawm interdialysis, thawj koob tshuaj 30mg tuaj yeem muab ua ntej pib lim ntshav. Txhawm rau kom tswj tau cov ntshav cov tshuaj concentration ntawm qib kev kho mob, koob tshuaj 30mg yuav tsum tau muab tom qab txhua qhov lim ntshav. Rau peritoneal dialysis cov neeg mob, nws raug nquahu kom muab cov khoom no 30mg ua ntej lim ntshav, thiab tom qab ntawd 30mg txhua hnub rau 5 hnub (saib [Pharmacokinetics] thiab [Kev Ceeb Toom]). Pharmacokinetics ntawm oseltamivir hauv cov neeg mob uas muaj kab mob raum kawg (xws li creatinine tshem tawm.<10ml/min) without dialysis has not been studied. Therefore, it is not possible to provide suggestions on the dosage of this kind of patients.
Kev tiv thaiv kab mob khaub thuas: nws tsis tsim nyog los kho cov koob tshuaj rau cov neeg mob uas muaj creatinine tshem tawm ntau dua 60 ml / min. Rau cov neeg uas nws qhov kev tshem tawm creatinine ntau dua 30ml / min tab sis tsis ntau dua 60ml / min, cov tshuaj pom zoo raug txo rau 30mg txhua zaus, ib hnub ib zaug. Rau cov neeg uas nws qhov kev tshem tawm creatinine ntau dua 10ml / min tab sis tsis ntau dua 30ml / min, cov tshuaj pom zoo raug txo rau 30mg txhua zaus, ib zaug ib hnub. Rau cov neeg mob hemodialysis li niaj zaus, yog tias cov tsos mob khaub thuas hnyav dua li ntawm 48 teev thaum lub sij hawm interdialysis, thawj koob tshuaj 30mg tuaj yeem muab ua ntej pib lim ntshav. Txhawm rau kom tswj tau cov ntshav cov tshuaj concentration ntawm qib kev kho mob, koob tshuaj 30mg yuav tsum tau muab tom qab txhua ob zaug kev lim ntshav. Rau peritoneal dialysis cov neeg mob, nws raug nquahu kom muab cov khoom no 30mg ua ntej lim ntshav, thiab tom qab ntawd 30mg txhua hnub rau 7 hnub (saib [Pharmacokinetics] thiab [Kev Ceeb Toom]). Pharmacokinetics ntawm oseltamivir hauv cov neeg mob uas muaj kab mob raum kawg (xws li creatinine tshem tawm.<10ml/min) without dialysis has not been studied. Therefore, it is not possible to provide suggestions on the dosage of this kind of patients.
Cov neeg mob uas muaj lub siab tsis txaus:
Cov koob tshuaj siv rau kev kho mob thiab tiv thaiv kab mob khaub thuas hauv cov neeg mob uas mob me thiab mob siab tsis txaus tsis tas yuav hloov kho (saib [Pharmacokinetics]). Kev nyab xeeb thiab tshuaj pharmacokinetics ntawm cov khoom no rau cov neeg mob uas mob siab tsis txaus tsis tau kawm.