Shikonin/Alkanin--Tshiab Nrov Khoom nyob rau hauv Anti-cancer Field

Shikonin / Alkanin yog dab tsi?

Shikonin yog ib hom organic teeb meem, tshuaj formula yog C16H16O5, nrog insoluble nyob rau hauv dej, soluble nyob rau hauv ethanol, organic solvents thiab zaub roj, soluble nyob rau hauv alkali dej, kua qaub thiab nag lossis daus. Nws yog purplish liab naphthoquinone ntuj pigment muab rho tawm los ntawm cov nroj tsuag ntuj Zongfugen. Cov khoom tseem ceeb yog Porphyroquinone thiab nws cov kab mob npe. Xws li Shikonin, acetochrome, B, P'-dimethylacryl Shikonin (P, P'-dimethylacryl Shikonin), P hydroxyisovaleryl Shikonin (P-hydaro-xyisovaleryl Shikonin), isovaleryl Shikonin, deoxy Shikonim, thiab lwm yam.

Khoom Specification

Dab tsi's covMuaj nuj nqintawm Shikonin?

(1) Cov nyhuv Hypoglycemic Cov extracts ntawm Lithosperms nplooj thiab comfrey polysaccharides (A, B, C) tag nrho muaj cov nyhuv hypoglycemic.

(2) Bacteriostatic effect S. chinensis muaj inhibitory nyhuv ntawm jingke 68-1 tus kab mob nyob rau hauv lub xeem tube thiab staphylococcus aureus. Cov teebmeem ntawm levochromatin ntawm tus kab mob parainfluenza tau kawm los ntawm hemagglutination cov tshuaj tiv thaiv thiab cytopathic assay. Cov txiaj ntsig tau pom tias levochromatin muaj toxicity tsawg nyob rau hauv qhov ntau ntawm cov concentration siv hauv kev sim, thiab muaj qee yam kev tiv thaiv kab mob khaub thuas ua haujlwm hauv vitro thiab ncaj qha tua tus kab mob parainfluenza.

(3) Cov nyhuv ntawm hemagglutination Intraperitoneal txhaj tshuaj ntawm cov xim xim (Shiverin, acetoshiverin) tsis cuam tshuam rau lub sijhawm ntawm cov ntshav coagulation, tab sis tuaj yeem tiv thaiv cov nyhuv anticoagulant ntawm heparin.

(4) Antitumor nyhuv Cov extract ntawm S. chinensis tuaj yeem inhibit DNA synthesis lig (G2 theem) ntawm Hela hlwb.

(5) Anticancer nyhuv Shiverin inhibits proliferation, txhawb apoptosis thiab induces cell voj voog ntes ntawm tib neeg choriocarcino-resistant cell kab (JAR / MTX) kab lis kev cai nyob rau hauv vitro. Cov txiaj ntsig kev sim tau pom tias qhov inhibition tus nqi ntawm shiverin ntawm kev loj hlob ntawm choriocarcino-resistant cell kab tau nce ntau nrog kev nce ntawm Chemicalbook concentration thiab ncua sij hawm ua haujlwm.

(6) Cov nyhuv ntawm Shiverin ntawm kev ua haujlwm ntawm hypothalamic-pituitary-gonad axis hauv cov hluas poj niam nas. Cov txiaj ntsig tau pom tias cov tshuaj hormones hauv cov ntshav hauv Shiverin pawg tau qis dua li hauv pawg tswj hwm tsis zoo, thiab tsis muaj qhov sib txawv tseem ceeb piv nrog pawg tswj hwm zoo. Cov txiaj ntsig tau pom tias shikonin inhibited kev ua haujlwm ntawm hypothalamic-pituitary-gonad axis hauv nas.

(7) Antioxidant kev ua haujlwm Lub peev xwm tshem tawm cov xim ntawm superoxide dawb radical (O2-) thiab 1, 1-diphenyl-2-picrhenazid dawb radical (DPPH) thiab nws cov nyhuv inhibitory ntawm autooxidation Qhov system ntawm -carotene / linoleic acid tau txiav txim siab. Cov txiaj ntsig tau pom tias cov xim ntawm S. chinensis muaj peev xwm khawb tau zoo ntawm DPPH thiab O2-, thiab inhibited -carotene / linoleic acid autooxidation system, qhia tias cov tshuaj pharmacological ntawm S. chinensis tej zaum yuav cuam tshuam rau cov antioxidant zog. muaj peev xwm ntawm naphthoquinone pigments.

Daim ntawv thov

Shikonin tuaj yeem siv rau hauv kev kho mob, kev kho mob, tshuaj pleev ib ce thiab zaub mov.

Peb tuaj yeem muab feem ntau ntawm cov khoom xyaw tshuaj nquag (APIs) rau cov neeg siv khoom, Yog tias koj muaj lus nug lossis xav paub ntau ntxiv, thov hu rau peb ntawm E-mail:info@haozbio.com