Pharmacological Action Ntawm Furacilin

Feb 24, 2023

【Cov ntsiab lus】

Nitrofuran, tshuaj lub npe 5-nitro-2-furan formaldehyde semicarbazone, alias furanxin; furan hnub qub; nitrofuran hydrazone; furacillin; Broad-spectrum antibacterial tshuaj, uas feem ntau siv cov tshuaj tiv thaiv kab mob, tuaj yeem cuam tshuam nrog cov txheej txheem qab zib metabolism thiab oxidase system ntawm cov kab mob kom tawm tsam cov kab mob los yog cov kab mob bactericidal. Lawv feem ntau cuam tshuam rau theem pib ntawm cov kab mob qab zib metabolism, ua rau cov kab mob metabolic tsis zoo thiab tuag. Nws yog dav thiab muaj cov kab mob tua kab mob ntawm ntau yam kab mob Gram-zoo thiab tsis zoo. Nws tuaj yeem tiv thaiv thiab kho cov kab mob sib kis xws li gastroenteritis, cholera thiab coccidiosis hauv cov tsiaj. Nws tau dav siv los ua khoom noj khoom haus. Nws yog dav siv nyob rau hauv kev kho mob ntawm plab hnyuv kab mob thiab lwm yam kab mob nyob rau hauv aquaculture.

【Lub cev thiab tshuaj muaj zog】

Txiv qaub daj zoo crystalline hmoov, tsw tsw, iab saj. Sensitive rau lub teeb, xim maj mam tig daj daj nyob rau hauv tshav ntuj. me ntsis soluble nyob rau hauv dej, me ntsis soluble nyob rau hauv ethanol, yooj yim soluble nyob rau hauv polar organic solvents, xim maj mam tig tsaus xim av thaum yaj nyob rau hauv alkaline tov, thiab pH ntawm saturated aqueous tov yog 5.5-7.5. Melting point 236-240 degree .

【Pharmacological kev txiav txim】

Furazone tuaj yeem cuam tshuam nrog cov txheej txheem qab zib metabolism thiab oxidase system ntawm cov kab mob ua kom muaj cov kab mob bacteriostatic lossis cov kab mob bactericidal. Nws feem ntau cuam tshuam rau theem pib ntawm cov kab mob qab zib metabolism, ua rau cov kab mob metabolic tsis zoo thiab tuag. Nws muaj cov kab mob dav dav, muaj cov kab mob tua kab mob ntawm ntau yam kab mob Gram-zoo thiab tsis zoo, thiab muaj cov nyhuv ntawm cov kab mob anaerobic. Nws tsis muaj txiaj ntsig tiv thaiv cov kab mob thiab cov pwm, tab sis nws tseem muaj txiaj ntsig zoo tiv thaiv kab mob los ntawm pwm. Cov bactericidal concentration rau cov kab mob rhiab heev yog 13-20ug/mL, thiab bacteriostatic concentration yog 5-10ug/mL.

【Indications】

Furazone yog siv sab nraud rau kev kho mob ntawm qhov txhab, kub hnyiab, suppurative dermatitis, otitis media, dacryocystitis, vaginitis, zais zis irrigation, bedsores, thiab lwm yam. Kab mob ntawm daim tawv nqaij rot ( kab mob luam ntawv), kab mob kab mob gill rot, kab mob ntawm daim tawv nqaij liab (hemorrhagic putrefaction), kab mob kab mob kis kab mob ntsug kab mob, kab mob fin rot thiab kab mob kab mob, kab mob ntawm daim tawv nqaij thiab congestion, kab mob khaub thuas, kab mob hauv qhov tsua, kab mob ntawm lub qhov ncauj dawb.

【Daim ntawv thov】

1. Rau kev kho mob thiab kev tiv thaiv ntawm tib neeg cov kab mob, xws li: rau kev kho mob ntawm myelitis ntev, cervical erosion, neeg laus omphalitis, senile aspiration pneumonia thiab hais txog.

2. Raws li kev pub khoom noj ntxiv, nws tau siv dav hauv cov tsiaj nyeg, nqaij qaib, muv thiab aquaculture.

3. Nws tuaj yeem kho thiab tiv thaiv kab mob plab, coccidiosis, nqaij qaib cholera, thiab lwm yam.

4. Furacilin feem ntau yog siv hauv kev kho mob hauv zos. Nws cov tshuaj tua kab mob muaj nyob hauv cov qauv uas tsis yog-ionic thiab tsis cuam tshuam los ntawm pH tus nqi ntawm lub cev kua. Tshwj tsis yog tias nws tsis muaj txiaj ntsig tiv thaiv Pseudomonas aeruginosa, nws txaus los tua cov kab mob feem ntau uas ua rau mob kis kab mob, thiab tsis tshua muaj tshuaj tiv thaiv. . Soaking lub urinary catheter nrog nitrofurazone tuaj yeem tiv thaiv qhov tshwm sim ntawm cov kab mob urinary uas tshwm sim los ntawm cov catheter hauv tsev, thiab qhov kub thiab txias thiab cov tshuaj tua kab mob siab tsis cuam tshuam rau cov tshuaj tua kab mob thiab cov ntsiab lus ntawm nitrofurazone ntawm cov zis catheter. Kev siv tshuaj pleev xim ntawm nitrofurazone tuaj yeem kho thiab tiv thaiv qhov txhab mob, xws li pyoderma, Ⅱ thiab Ⅲ degree kub hnyiab, daim tawv nqaij grafts thiab kis kab mob hauv chaw pub dawb. Kev kho mob bacillary dysentery nrog nitrofurazone kua enema, kev kho mob plab tsis pom tseeb, tab sis cov nyhuv ntawm cov tshuaj tiv thaiv kab mob yog qhov zoo kawg.

【Dosage】

Daim ntawv thov tshuaj pleev: {{0}}.01 feem pua rau 0.{{10}} 2 feem pua tshuaj rau ntawm qhov txhab rau kev ntxuav los yog ntub compressed. 0.2% ~ 1% ointment txheej. Compound nitrofurazone qhov ntswg tee muaj 0.02 feem pua ntawm cov khoom no thiab 1 feem pua ntawm ephedrine hydrochloride, thiab yog siv rau qhov ntswg te. Nws 0.001 feem pua ~ 0.005 feem pua tuaj yeem siv tau rau gargling.

Tsuas yog hu rau peb ntawm email:info@haozbio.comrau tej lus nug.