Ivermectin hmoov

Hauj lwm lawm

Cov lus qhia luv luv ntawm Ivermectin hmoov:

Ivermectin yog ib tug tshiab broad-spectrum, high-efficiency, low-toxicity tshuaj tua kab mob antiparasitic tshuaj, uas muaj ib tug zoo tua nyhuv rau sab hauv thiab sab nraud parasites, tshwj xeeb tshaj yog nematodes thiab arthropods. Tab sis nws yog ineffective tiv thaiv tapeworms, flukes thiab protozoa.

Specification ntawmIvermectin hmoov:

Muaj nuj nqi ntawmIvermectin hmoov:

Cov nyhuv repelling ntawm macrolide antiparasitic tshuaj ntawm nematodes thiab arthropods yog ua kom tso tawm ntawm inhibitory transmitter -aminobutyric acid (GABA) ntawm cov cab, thiab qhib Cl ion channel tswj los ntawm glutamate, Txhim kho cov permeability ntawm cov paj hlwb rau Cl. , yog li thaiv kev sib kis ntawm cov paj hlwb, thaum kawg cov hlab ntsha tuag tes tuag taw, kom cov leeg nqaij tsis muaj peev xwm cog lus, ua rau tus kab mob tuag.

Vim hais tias flukes thiab tapeworms tsis siv GABA raws li ib tug transmitter thiab tsis muaj Cl raws tswj los ntawm glutamate, chav kawm ntawm cov tshuaj no tsis zoo. Lub peripheral neurotransmitter ntawm cov tsiaj nyeg yog acetylcholine. Txawm hais tias GABA tau muab faib rau hauv lub hauv nruab nrab lub paj hlwb, hom tshuaj no tsis yooj yim rau nkag mus rau hauv cov ntshav-hlwb barrier thiab muaj kev cuam tshuam me ntsis rau nws, yog li nws muaj kev nyab xeeb rau kev siv.

Cov txheej txheem ntawm cov tshuaj no cuam tshuam rau kev tsim cov kab mob cab kuj tsis nkag siab zoo, tab sis nws tuaj yeem txo cov oviposition hauv cov zuam, lub qe txawv txav ntawm cov ruminant nematodes thiab sterility ntawm filamentous nematodes (txiv neej thiab poj niam).

Daim ntawv thov ntawmIvermectin hmoov:

Ivermectin yog dav siv nyob rau hauv gastrointestinal nematodes, ntsws nematodes thiab parasitic arthropods ntawm nyuj, yaj, nees thiab npua, plab hnyuv nematodes nyob rau hauv dev, pob ntseg mites, scabies mites, heartworms thiab microfilariae, thiab nqaij qaib plab plab nematodes thiab ecto.

(1) nyuj thiab yaj

Ivermectin yog siv los ntawm qhov ncauj lossis subcutaneously rau nyuj thiab yaj ntawm ib koob ntawm 0.2 mg / kg. Qhov ncauj nematodes, nematodes, trichomes, esophagus qhov ncauj nematodes, reticulate nematodes, thiab Charbert nematodes cov neeg laus thiab plaub-theem larvae, thiab deworming tus nqi yog 97% mus rau 100 feem pua. Cov koob tshuaj saum toj no kuj muaj txiaj ntsig zoo rau cov kab mob arthropods: xws li yoov maggots (Noj fav, nyuj, yaj, yaj), mites (Bovine scabies, prurigo) thiab ntshauv (Bovine palatal lice, bovine blood louse thiab sheep palatal Louse) Tos. Ivermectin tsis tshua muaj txiaj ntsig tiv thaiv kev zom plav (Liceus spp.) thiab yaj zuam yoov.

Ivermectin kuj zoo heev tiv thaiv zuam thiab yoov uas yug hauv quav. Txawm hais tias cov tshuaj tsis tua cov zuam tam sim ntawd, nws tuaj yeem cuam tshuam rau kev pub mis, molting, thiab qe nteg, yog li txo qhov muaj peev xwm ntawm kev tsim me nyuam. Qhov tshwm sim saum toj no tau pom tseeb tshaj plaws hauv cov zuam thaum cov tsiaj tau txhaj tshuaj subcutaneous ntawm {{0}}.2 mg / kg ib zaug lossis noj cov tshuaj tsis muaj zog (0.01 mg / kg) txhua hnub rau 5 hnub. Kev txhaj tshuaj subcutaneous ntawm ib koob ntawm 0.2 mg / kg kuj muaj qee yam kev tswj xyuas cov yoov uas yug hauv cov quav. Tom qab 9 hnub ntawm kev tswj hwm tshuaj, cov larvae ntawm cov quav thiab cov yoov ntawm faecium tsis tuaj yeem loj hlob mus rau cov neeg laus. Tom qab lwm 5 hnub, vim qhov txawv txav ntawm cov pupae thiab cov txheej txheem loj hlob ntawm cov neeg laus yoov yog hindered thiab kev loj hlob ntawm yoov yog heev txo. Cov koob tshuaj saum toj no tau siv rau cov ntshav yoov (cov ntshav yoov), thiab qhov xwm txheej zoo sib xws tom qab 4 lub lis piam.

(2) Nees

Kev tswj qhov ncauj ntawm {{0}}.2 mg/kg ivermectin hauv nees yog qhov ua tau zoo (95 feem pua ​​​​rau 100 feem pua) rau cov neeg laus thiab plaub-theem larvae ntawm cov nram qab no loj thiab me me puag ncig nematodes; nematodes, roundworms), roundworms (paraascaris equine), pinworms (equinox equine), plab worms (Draxiella maxima, D. elegans), plab hnyuv nematodes (T. Strongyloides Wechnerii), ntsws nematodes (Reichthys angelica), thiab lwm yam. hom equine plab ya maggots nyob rau hauv lub migration los yog gastric residence lub sij hawm, lub onchocerciasis microfilariae uas ua rau cov tawv nqaij puas thiab lub thib peb theem larvae ntawm gastric nematodes, txawm hais tias tus nqi ntawm 0.2 mg / kg thov nyob rau hauv ib lub sij hawm kuj yog heev txwv, qhov zoo tshaj plaws tov. yog Nws yuav tsum tau muab tshuaj ntxiv rau hauv cov nyiaj saum toj no tom qab ib hlis.

Nws yog qhov tseem ceeb tshwj xeeb uas qhov pom zoo koob tshuaj ivermectin (0.2mg/kg) yog li ntawm 99 feem pua ​​​​zoo hauv kev kho cov hlab ntsha mesenteric uas tshwm sim los ntawm theem pib thiab thib plaub larvae ntawm Oryx vulgaris, thiab cov tshuaj li niaj zaus 2 Hnub. Tom qab ntawd, cov tsos mob tau txo qis, thiab cov tsos mob ntawm kev puas tsuaj ploj mus li ntawm 28 hnub.

(3) npua

Intramuscular txhaj ntawm 0.3 mg/kg ivermectin muaj broad-spectrum anthelmintic kev ua si hauv npua. Xws li Ascaris suum, Strongylargi suis, Strongyloides lansii, Trichocarpus nematodes, Esophagus nematodes, Strongyloides esophagus, Cristina dentatus cov neeg laus thiab cov kab mob tsis paub qab hau, qhov kev tshem tawm yog 94 feem pua ​​​​rau 100 feem pua. Intratracheal Trichinella (tsis ua haujlwm hauv cov leeg) kuj zoo heev. Txoj kev hais saum toj no kuj muaj kev tswj xyuas zoo ntawm cov ntshauv npua thiab npua kab mob mites.

(4) Cov dev thiab miv

Muaj cov txheej txheem tshwj xeeb hauv txawv teb chaws (raws li 6-12 ug/kg) rau kev tiv thaiv thiab kho tus kab mob canine heartworm microfilaria. Hauv kuv lub tebchaws, 50 ug / kg ntawm kev tswj qhov ncauj tuaj yeem siv los kho cov kab mob plawv microfilaria (cov neeg laus tsis raug cai). Kev sim tshuaj kho mob tau lees paub tias koob tshuaj ivermectin muaj txiaj ntsig zoo tiv thaiv ntau yam kab mob hauv cov dev, xws li kev txhaj tshuaj subcutaneous ntawm 50ug / kg rau Ancystoma canis, Anchostomia brasiliensis, thiab Ancylostoma canis, thiab 100ug / kg rau Trichuris canis , 200ug / kg ntawm Toxocara canis neeg laus thiab plaub theem larvae muaj kev tsav tsheb zoo heev. Rau Toxocara tsov ntxhuav, raws li koob tshuaj ntawm 200ug / kg, cov nyhuv ntawm kev txhaj tshuaj subcutaneous tsuas yog 69 feem pua, thaum lub qhov ncauj tswj hwm yog 95 feem pua. Ib qho kev txhaj tshuaj subcutaneous ntawm cov khoom no kuj muaj cov txiaj ntsig zoo ntawm kev tshem tawm Capillary nematodes (200ug / kg) thiab Ostleria ausleri (400ug / kg) parasitic nyob rau hauv lub ntsws ntawm dev. Qhov ncauj lossis subcutaneous txhaj ntawm 200 ug / kg, thiab tom qab ntawd ib zaug tom qab ob lub lis piam, muaj qhov ua tau zoo ntawm 95 feem pua ​​​​rau 100 feem pua ​​​​ntawm cov hnyuv Strongyloides stercoralis (tshwj tsis yog cov kab mob thib peb).

Ivermectin kuj tseem siv tau rau qee yam kab mob arthropod hauv dev thiab miv. Kev txhaj tshuaj subcutaneous ntawm 200ug / kg hauv dev thiab miv, thiab ib zaug ntxiv tom qab ob lub lis piam tuaj yeem tshem tawm cov kab mob pob ntseg, kab mob kab mob, thiab kab mob ntsws. Ntawm 300ug / kg, nws kuj zoo heev rau kev kis kab mob ntawm Chia chelae mites thaum siv ob zaug (2 lub lis piam sib nrug). Kev kho mob ntawm canine demodicosis yog qhov zoo tshaj plaws los ntawm kev txhaj tshuaj subcutaneous ntawm 600ug / kg, nrog rau lub sijhawm ntawm 7 hnub. Siv 5 zaug ua ke.

(5) Nqaij qaib

Nws muaj txiaj ntsig zoo rau cov nqaij qaib nematodes xws li Ascaris ascaris thiab capillary nematodes thiab parasitic arthropods ntawm cov nqaij qaib, xws li hauv caug mites (mutant Knee mites), thiab lwm yam. Txawm li cas los xij, cov khoom no tsis zoo rau Heterospinus hens.

(6) Reindeer

Txhawm rau kis tus kab mob reindeer nkaum ya maggot (Oedemagena tarandi), txhaj tshuaj subcutaneous tuaj yeem ua tiav raws li koob tshuaj bovine (200ug / kg).

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Vim li cas thiaj xaiv peb:

Peb yog cov chaw tsim khoom thiab cov kws tshawb fawb rau cov khoom siv tshuaj, cov khoom siv cog qoob loo, kev kho mob raws li ntau tshaj 8 xyoo. Peb tau koom tes nrog cov neeg siv khoom los ntawm Tuam Tshoj, Tebchaws Asmeskas, Europe, Middle East, Southeast Asia thiab lwm thaj chaw.

Noj qab nyob zoo, hluas, mob siab rau thiab kev pab yog peb tenet.

Peb muaj ntau cov khoom tiv thaiv plaub hau, yog tias muaj kev txaus siab, thov hu rau peb ntawm email hauv qab no:

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