Clomipramine

Whntawm'Puas yog Clomipramine?

Clomipramineyog ib qho kev nyab xeeb thiab txhim khu kev qha tricyclic antidepressant nrog kev ua haujlwm sai. Nws yog dawb los yog daj crystalline hmoov nyob rau hauv chav tsev kub. Tsis hnov ​​tsw, iab saj; Lub teeb xim hloov mus rau daj. Nws yog heev soluble nyob rau hauv glacial acetic acid los yog chloroform, yooj yim soluble nyob rau hauv dej los yog ethanol, me ntsis soluble nyob rau hauv acetone, thiab yuav luag insoluble nyob rau hauv ether.

Synonym

g34586; Hydiphen; Monochlorimipramine; RARECHEM AX KI 5027; CLOMIPRAMINE HYDROCLORIDE; AURORA KA-7606; Chlorimipramine; Chlorimipramine HYDROCHLORIDE

PKhoom Specification

Khoom npe:	Clomipramine	CAS Nr .:	303-49-1
Molecular Luj:	314.85	EINECS:	206-144-2
Formula:	C19H23ClN2	Ceev:	1.0568 (zeeg)

Ftsis ua haujlwm

Clomipraminetsim cov tshuaj tiv thaiv kev nyuaj siab los ntawm inhibiting reuptake ntawm norepinephrine (NA) thiab 5-hydroxytryptamine (5-HT) nyob rau hauv cov ntaub so ntswg presynaptic, nrog rau cov teebmeem anxiolytic thiab sedative. Cov nyhuv inhibitory ntawm 5-hydroxytryptamine reuptake muaj zog dua li lwm cov tshuaj tricyclic, thaum cov nyhuv inhibitory ntawm norepinephrine reuptake tsawg dua li ntawm imipramine thiab amitriptyline. Nws cov nyhuv anticholinergic yog nruab nrab thiab nws cov nyhuv sedative tsawg. Nws yog absorbed zoo tom qab noj qhov ncauj. Kev kho cov ntshav siab yog 200-500ng / ml, thiab cov ntshav nyob ruaj khov tuaj yeem ncav cuag hauv 1-2 lub lis piam. Tom qab cov metabolism hauv hepatic, qhov concentration ntawm cov nquag metabolite norclomipramine yog ob npaug ntawm cov tshuaj qub. Cov plasma protein khi tus nqi yog 96Chemicalbook ~ 97%, thiab ib nrab-lub neej yog 21 ~ 31 teev. Kwv yees li 70% yog tawm hauv cov zis thiab 30% yog tawm hauv cov quav. Nws yog haum rau kev kho mob ntawm endogenous, reactive, neurological, latent kev nyuaj siab thiab ntau yam kev nyuaj siab lub xeev; schizophrenia nrog kev nyuaj siab; obsessive-compulsive teeb meem, phobia; ntau yam mob, thiab lwm yam. Cov tshuaj kuj tseem tuaj yeem txo cov qib ntawm 5-hydroxyindoleacetic acid (5HIAA) hauv cov kua cerebrospinal thiab platelets, uas muaj feem xyuam rau cov tshuaj muaj peev xwm los kho obsessive-compulsive teeb meem. Nws muaj affinity rau D2 receptors, alpha-adrenergic receptors, thiab histamine receptors. Tsis tas li ntawd, nws muaj zog anticholinergic cov teebmeem thiab me me dopamine antagonism uas tuaj yeem nce qib plasma ntawm prolactin thiab kev loj hlob hormone.

Cov tshuaj sib cuam tshuam

Kev siv nrog ethanol tuaj yeem ua rau muaj kev nyuaj siab hauv lub paj hlwb.

Kev siv nrog cov tshuaj tiv thaiv kab mob tuaj yeem txo qis tus neeg mob qaug dab peg, yog li txo cov nyhuv ntawm cov tshuaj tiv thaiv kab mob, thiab cov tshuaj tiv thaiv kab mob yuav tsum tau hloov kho.

Thaum siv ua ke nrog cov tshuaj antihistamines lossis anticholinergics, cov tshuaj cuam tshuam yuav ntxiv dag zog rau ib leeg, thiab cov tshuaj yuav tsum tau hloov kho raws sijhawm.

Thaum siv guanethidine thiab clomipramine ua ke, cov nyhuv antihypertensive ntawm yav dhau los yuav raug txo. Txawm li cas los xij, thaum qhov ntau npaum li cas tsis tshaj 150mg ib hnub, qhov ua tau zoo ntawm guanethidine yuav tsis cuam tshuam los ntawm Chemicalbook.

Thaum siv ua ke nrog cov tshuaj estrogen lossis estrogen-muaj cov tshuaj tiv thaiv kab mob, nws tuaj yeem ua rau muaj qhov tsis zoo ntawm clomipramine thiab txo cov tshuaj tiv thaiv kev ntxhov siab.

Kev siv ua ke nrog monoamine oxidase inhibitors tuaj yeem ua rau muaj kev kub ntxhov, thiab kev tuag tau tshaj tawm. Feem ntau, cov qub yuav tsum tau nres rau ob lub lis piam ua ntej siv.

Kev siv ua ke nrog adrenergic receptor agonists tuaj yeem ua rau mob ntshav siab thiab kub taub hau.

Kev siv ua ke nrog cov thyroid npaj tuaj yeem sib koom ua ke thiab ua rau arrhythmia, yog li qhov ntau npaum li cas ntawm ob qho tib si yuav tsum raug txo.

Daim ntawv thov

Clomipramine tuaj yeem kho ntau yam kev nyuaj siab; kho obsessive-compulsive neurosis thiab phobic neurosis.

Ntim & Xa

Cargo hnyav	Ntim	Shipping txoj kev	Lead-time
5-50kg	Hauv qab 5kg Siv Foil hnab;5-25kg siv ob txheej PP hnab, ces mus rau hauv lub thawv master lossis cardboard nruas	International nthuav qhia	7-10hnub
100-200kg	25kg/nruas, siv ob txheej PP hnab, ces mus rau hauv cardboard nruas	Huab cua shipping	7-10hnub
Ntau tshaj 500 kg	25kg/nruas, siv ob txheej PP hnab, ces mus rau hauv cardboard nruas	Hiav txwv shipping	20-45hnub

Feem ntau cov ntim yog 25kg / nruas; tshaj 50kg peb tuaj yeem nkoj los ntawm huab cua; tshaj 100kg peb tuaj yeem nkoj los ntawm hiav txwv.

FAQ

1. Kuv puas tuaj yeem tau txais qee qhov qauv dawb?

Yog, peb tuaj yeem muab cov qauv dawb ntawmClomipramine, tab sis tus nqi thauj khoom yuav raug them los ntawm cov neeg siv khoom.

2. Lub sijhawm them nyiaj yog dab tsi?

Kev them nyiaj tuaj yeem ua tiav los ntawm T / T, Credit Card, Western Union, PayPal thiab ntau dua.

3. Koj lub Hoobkas ua li cas kom paub tseeb tias cov khoom zoo?

Peb muaj txog 10 xyoo dhau los hauv daim teb no, peb twb muaj cov txheej txheem tswj kom paub tab. Tsis tas li ntawd peb yuav ua qhov kawg kuaj ua ntej shipping kom tsis txhob muaj teeb meem.

4. Koj puas tuaj yeem ua OEM rau kuv?

Peb txais OEM xaj.

5. Yuav tiv tauj peb li cas?

Koj tuaj yeem tham nrog peb ntawm email, Whats-App lossis tsuas yog xa email rau peb, hu xov tooj. Tag nrho peb cov kev sib cuag tau pom hauv lub vev xaib.

Peb tuaj yeem muab ntau yam tshuaj tiv thaiv kev nyuaj siab rau cov neeg siv khoom, Yog tias koj muaj lus nug lossis xav paub ntxiv, thov hu rau peb ntawm E-mail:info@haozbio.com

 

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