Emodin hmoov

Hauj lwm lawm

Dab tsi yog Emodin hmoov?

Emodinyog ib yam ntawm cov organic teeb meem, tshuaj formula yog C15H10O5, txiv kab ntxwv daj ntev koob siv lead ua, siv lead ua txiv kab ntxwv nyob rau hauv acetone, crystal daj nyob rau hauv methanol, melting point 256 degree ~ 257 degree, muaj ib tug tshwj xeeb cov tshuaj tiv thaiv ntawm anthraquinone, yuav luag insoluble nyob rau hauv dej, soluble nyob rau hauv ethanol thiab alkali tov.

Emodin yog lub ntuj tsim tawm los ntawm Suav tshuaj ntsuab xws li Rhubarb thiab Polycuspidum cuspidatum, uas muaj cov tshuaj tua kab mob, tshuaj tua kab mob, tiv thaiv qog thiab lwm yam tshuaj. Emodin feem ntau yog siv rau tshuaj tua kab mob, tshuaj tiv thaiv kab mob, tshuaj tiv thaiv kev hloov pauv, ANTI-corrosion, tiv thaiv qog noj ntshav (hauv siab), tiv thaiv kab mob, tiv thaiv kab mob, catharsis, gonadotropin, tshuaj tiv thaiv kab mob, tshuaj tua kab, laxative, spasMODIc, hemostatic agent. .

Synonym

CI 75440; CI Ntuj Yellow 14; Emodin; 1,3,8-Trihydroxy-6-methylanthraquinone; 6-Methyl-1,3,8-trihydroxyanthraquinone; emodin los ntawm frangula bark.

Khoom Specification

Muaj nuj nqi

1, Antitumor kev ua haujlwm

Emodin muaj inhibitory cuam tshuam rau cov khoom sarcoma S-180, mob qog noj ntshav, mob cancer mis, Ehrsson ascites carcinoma, lymphosarcoma, melanoma, Wackeroma thiab mob ntsws cancer A-549 hauv cov nas, thiab tus nqi inhibitory yog ntau tshaj 30 feem pua. . Ntawm koob tshuaj 50mg / kg txhua hnub -1, qhov inhibition ntawm melanoma loj hlob hauv nas yog 73 feem pua. Tus nqi inhibition ntawm mob qog noj ntshav hauv cov nas yog 45 feem pua ​​​​ntawm 75mg / kg txhua hnub -1 koob. Emodin tuaj yeem ua kom muaj sia nyob ntawm P388 leukemia nas ntau dua 40 feem pua. Ib qho ntawm nws cov txheej txheem yog inhibition ntawm DNA, RNA thiab protein biosynthesis hauv cov qog nqaij hlav cancer, thiab inhibition ntawm oxidative dehydrogenation hauv cov qog nqaij hlav cancer.

2, Anti-microbial kev loj hlob nyhuv

Emodin muaj cov teebmeem inhibitory ntawm Staphylococcus aureus 209P, Streptococcus, Bacillus diphtheriae, Bacillus subtilis, Bacillus paratyphoid, Bacillus dysenteriae, Escherichia coli, Bacillus influenzae, pneumococcus thiab Catarlococcus. Nws muaj zog inhibitory nyhuv ntawm kev kho mob anaerobic kab mob. Nws MIC yog me ntsis siab dua metronidazole, thiab nws tuaj yeem cuam tshuam kev loj hlob ntawm 76 feem pua ​​~ 91 feem pua ​​​​ntawm cov kab mob anaerobic ntawm 8ug / mL concentration. Cov tshuaj tiv thaiv kab mob ntawm emodin muaj feem xyuam rau inhibition ntawm electron thauj hauv mitochondrial respiratory saw thiab oxidation thiab dehydrogenation ntawm metabolites ntawm amino acids, suab thaj thiab proteins. Qhov kawg tshwm sim ntawm inhibition ntawm nucleic acid thiab protein synthesis, kom cov kab mob loj hlob yog inhibited.

3, Immunosuppressive nyhuv

Intraperitoneal txhaj ntawm emodin ntawm ib koob ntawm 70mg / kg tuaj yeem inhibit qhov tsim cov tshuaj tiv thaiv kab mob, inhibit lub peev xwm tshem tawm cov pa roj carbon monoxide, txo qhov hnyav ntawm lub cev tiv thaiv kab mob, txo cov qe ntshav dawb, thiab txo cov phagocytosis muaj nuj nqi ntawm peritoneal macrophages. Hauv vitro, 10mg / ml concentration ntawm [3H] -tdr thiab [3H] -urd txhaj cov lymphocytes muaj qhov cuam tshuam loj heev.

4, Antispasmodic thiab antitussive teebmeem

Emodin muaj zog inhibitory nyhuv ntawm spasm ntawm cov kab mob ntawm cov nas uas nyob ib leeg raug ntxias los ntawm acetylcholine, uas yog kwv yees li 4 npaug ntawm papaverine. Emodin kuj tseem muaj cov tshuaj tiv thaiv hnoos tseem ceeb.

5, Kev cuam tshuam rau cov hlab plawv

Emodin muaj cov nyhuv excitatory ntawm lub plawv toad cais ntawm koob tshuaj tsawg, thaum nws muaj inhibitory nyhuv ntawm koob tshuaj ntau. Emodin kuj tseem muaj cov ntshav siab txo qis.

6, Diuretic nyhuv

Emodin tuaj yeem nce sodium thiab potassium hauv cov zis, txhawb ureteral peristalsis, nce zis ntim.

7, Cov nyhuv ntawm histamine

Thaum emodin tau noj ntawm koob tshuaj 10 ug / kg rau cov nas nrog kev sim plab hnyuv, cov ntsiab lus histamine hauv plab hnyuv mucosa ntawm nas tuaj yeem rov qab mus rau qhov qub, tab sis nws tsis cuam tshuam rau cov ntsiab lus histamine hauv cov ntshav.

8, LTB4 synthesis

Emodin yog ib qho inhibitor ntawm 5-lipoxygenase, uas tuaj yeem cuam tshuam cov synthesis ntawm LTB4 nyob rau hauv tib neeg multinucleated leukocytes thiab tag nrho cov ntshav, tab sis tsis muaj inhibitory nyhuv ntawm synthesis ntawm PGE2.

9, Nyob rau hauv cov nyhuv purging

Emodin tuaj yeem cuam tshuam cov sodium thiab potassium ions Los ntawm lub plab hnyuv lumen thauj mus rau hauv lub cell, ua kom cov dej khaws cia hauv plab hnyuv lumen, txhawb cov hnyuv loj, txhawb nqa nws cov PERISTALsis, yog li muaj kev ua raws plab, tab sis cov nyhuv tsis muaj zog.

Daim ntawv thov

Emodin tuaj yeem siv los ua laxative, txawm hais tias muaj cov haujlwm cathartic, tab sis vim tias lub cev yooj yim raug rhuav tshem los ntawm oxidation, cov nyhuv cathartic tsis muaj zog heev, yog tias ua ke nrog qab zib rau hauv glycosides, tuaj yeem ua si cathartic nyhuv. Emodin - 1-O- -D-glucoside thiab emodin - 8-O- -D-glucoside yog glycosides ntawm emodin thiab qabzib, tab sis lawv khi nyob rau hauv ntau qhov chaw thiab muaj nyob rau hauv rhubarb. Lwm cov tshuaj tua kab mob, hnoos, tiv thaiv qog, txo cov ntshav siab

Ntim & Xa

Feem ntau cov ntim yog 25kg / nruas; tshaj 50kg peb tuaj yeem nkoj los ntawm huab cua; tshaj 100kg peb tuaj yeem nkoj los ntawm hiav txwv.

FAQ

1. Kuv puas tuaj yeem tau txais qee qhov qauv dawb?

Yog, peb muab cov qauv dawb ntawmEmodin hmoovrau tus neeg siv khoom tab sis tus nqi thauj khoom yuav raug them los ntawm tus neeg siv khoom.

2. Yuav ua li cas them nyiaj thiab lub sijhawm them nyiaj yog dab tsi?

Kev them nyiaj tuaj yeem ua tiav los ntawm T / T, Credit Card, Western Union, PayPal thiab ntau dua.

3. Koj lub Hoobkas ua li cas kom paub tseeb tias cov khoom zoo?

Ua ntej tshaj plaws, peb muaj txog 10 xyoo kev paub hauv daim teb no, peb twb muaj cov txheej txheem tswj kom paub tab. Tsis tas li peb yuav kuaj zaum kawg ua ntej xa khoom kom tsis txhob muaj teeb meem.

4. Koj puas tuaj yeem ua OEM rau kuv?

Peb txais OEM xaj, tsuas yog tiv tauj peb thiab xa koj qhov kev thov rau peb. Peb yuav muab koj tus nqi tsim nyog thiab ua qauv ASAP.

5. Yuav tiv tauj peb li cas?

Koj tuaj yeem tham nrog peb los ntawm email, Skype thiab Whats-App lossis tsuas xa peb email, hu xov tooj. Tag nrho peb cov kev sib cuag tau pom hauv lub vev xaib.

Peb tuaj yeem muab cov khoom xyaw API feem ntau rau cov neeg siv khoom, Yog tias koj muaj lus nug lossis xav paub ntxiv, thov hu rau peb ntawm E-mail:info@haozbio.com

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